Terminalia Bellerica fruit extract

Lately, the focus of the work is on assessing the immunomodulatory effect of T. bellerica extract. Since different activities of the extract have been attributed to the various biologically active compounds present in it, it is likely that some of these influence the host immune system as well. Gallic acid of many different plant extracts has been reportedly responsible for increasing ROS production in macrophages resulting in their increased phagocytic activity . T. bellerica fruit extract is also rich in gallic acid content and therefore has been reported to be responsible for increasing the phagocytic activity of macrophages. The other mechanism for the enhanced phagocytic activity of the extract is due to some alteration in the mechanism of action of related enzyme such as phosphotyrosine phosphatase resulting in superoxide anion production.

Description

Terminalia bellerica fruit extract is applied externally to eyes. It is laxative, & is useful in diarrhea, piles,dyspepsia, biliousness, headache, inflammatory effect of small intestine. It is expectorant in coughs & inflammation of throat. It is also used in leprosy & dropsy & enlargement of spleen.

Additional information:

The extracts are delivered paraben free, and low bacterial count without the use of any chemical or gamma treatment. Amsar is a responsible manufacturer providing green eco friendly extracts and does not discharge solvents, gases or other hazardous materials into the environment.

Latin Name : Terminalia bellerica
Sanskrit Name : Vibhitaka
Common Name : Bahera
Family :Combrataceae
Part Plant Used : Fruit
Solvent Used : Hydrolic alcohol
Storage Condition : In Double Sealed PP Bags
Appearance : Brown Powder
Organoleptic Test : Astringent Taste
Odor : Characteristic Odor
Herb Ext. Ratio : 3:1
Water soluble extractives: Not less than 65%
Tannins by USSRP X assay taking 0.2 gram sample : above 25.5%

References

IPC 53, Pg.238
Indian Materia Medica, K.M.Nadkarni, Pg.1203
Major Medicinal Plants of India, CIMAP, Pg.493
Indian Drugs 26(12), Pg.655, M.A.Iyengar & S.Dwivedi
Handbook of Medicinal Plants, S.K.Bhattacharjee, 1998, Pg.343
Illustrated Manual of Herbal Drugs, CSIR & ICMR, 1996, Pg.212

Heavy Metals

A) Total Heavy Metals Not More Than 10ppm
B) As Not More Than 1ppm
C) Pb Not More Than 0.3ppm
D) Cd Not More Than 0.2 Ppm
E) Hg Not More Than 0.1 Ppm

Microbiological Profile

Total Plate Count : <1,000 Cfu/Gm
Mold : < 100 Cfu/Gm
Yeast : < 100 Cfu/Gm
E .Coli : Absent
Salmonella : Absent

Chemical constituents

gallotannic acid, ellagic acid, gallic acid, lignins such as termilignin and thannilignin and anolignan-B , 7-hydroxy-3, 4-flavone, ethyl gallate, galloyl glucose, chebulaginic acid, phenyllemblin, ß-sitosterol, anthraquinones, glycosides such as bellaricanin