Withania somnifera extract (Ashwagandha)

Centuries of Ayurvedic medical experience using Withania somnifera( Ashwagandha) have revealed it to have pharmacological value as an adaptogen, antibiotic, abortifacient, aphrodisiac, astringent, anti-inflammatory, deobstruent, diuretic, narcotic, sedative, and tonic. Ashwagandha has been found to provide potent antioxidant protection. Stimulate the activation of immune system cells, such as lymphocytes and phagocytes Counteract the effects of stress and generally promote wellness

Additional information:

The extracts are delivered paraben-free, and low bacterial count without the use of any chemical or gamma treatment. Amsar is a responsible manufacturer providing green eco-friendly extracts and does not discharge solvents, gases or other hazardous materials into the environment.

Latin Name : Withania somnifera
Sanskrit Name : Ashwagandha
Common Name : Winter cherry
Family : Solanaceae
Part Plant Used : Root
Solvent Used : Hydroalcohol
Storage Condition : In Double Sealed PP Bags
Appearance : Brown Powder
Organoleptic Test : Bitter
Odour : Characteristic Odour
Herb Ext. Ratio : 5:1
EXTRACTIVES I) IN WATER : Nlt 60%
Total Withanolides : NLT 2.5%
Alkaloids: NLT 0.8%

Chemical constituents

Laboratory analysis has revealed over 35 chemical constituents contained in the roots of Withania somnifera [9]. The biologically active chemical constituents are alkaloids (isopellertierine, anferine), steroidal lactones (withanolides, withaferins), saponins containing an additional acyl group (sitoindoside VII and VIII), and withanoloides with a glucose at carbon 27 (sitonidoside XI and X). Withania somnifera is also rich in iron. The roots of Withania somnifera consist primarily of compounds known as withanolides, which are believed to account for its extraordinary medicinal properties. Withanolides are steroidal and bear a resemblance, both in their action and appearance, to the active constituents of Asian ginseng (Panax ginseng) known as ginsenosides

References

Weiner, M.A, Weiner.J Ashwagandha (India ginseng). In: Herbs that Heal. Mill Valley, CA: Quantum Books,70–72;1994.

S. Sharma, S. Dahanukar, S.M. Karandikar. Effects of long-term administration of the roots of ashwagandha and shatavari in rats. Indian Drugs. 1985;133–139.

Budhiraja RD, Sudhir S. Review of biological activity of Withenolides (Antibacterial Antitumor, Immunomodulating, Antiinflammatory and insect anti feedcent). J Sci Ind Res. 46, 488-91.

Chopra, R.N. Glossary of Indian Medicinal Plants. New Delhi: Academic Publishers India; 1994.

Glotter E, Kirson I, Abraham A, Lavie D. Constituents of Withania somnifera Dun—13. The withanolides of chemotype III. Tetrahedron. 1973;29(10):1353–1364.

Devi PU, Sharada AC, Solomon FE. Antitumor and radios ensitizing effects of Withania somnifera (Ashwagandha) on a transplantable mouse tumor, Sarcoma- 180. Indian J Exp Biol. 1993;31(7):607-11

“Withania somnifera“. Alternative Medicine Review. FindArticles.com. 13 Oct. 2008.

Behl PN, Arora RB, Srivastava and Malhotra SC. Herbs Useful in Dermatological Therapy.;New Delhi :CBS Publishers and Distributors, 141-142; 1993.

Rastogi RP, Mehrotra BN, Compendium of Indian Medicinal Plants, Central Drug Research Institute, New Delhi, Vol. 6;1998.

Grandhi, A. Comparative pharmacological investigation of ashwagandha and Ginseng. J Ethnopharmacol (Ireland).1994;3:131-135