Aloe vera :
The miracle herb as it is known across the globe yields a variety of medicinally active compounds. Amongst the more important compounds from Aloe vera is a group known as anthraquinones of which Aloin forms a major part. Aloin is a proven purgative widely used in the field of medicine. Aloe contains at least three anti-inflammatory fatty acids that are helpful for the stomach, small intestine and colon. It naturally alkalizes digestive juices to prevent hyperacidity - a common cause of indigestion. It helps cleanse the digestive tract by exerting a soothing, balancing effect. In a study by Ishii Y et al, Aloe-emodin-9-anthrone(AE-anthrone), produced from barbaloin in the rat large intestine, caused not only an increase in the intestinal water content but also stimulated mucus secretion. This might play an important role in the occurrence of diarrhea. It was demonstrated that the amount of AE-anthrone produced in the rat large intestine(maximal amount: 568 micrograms/rat at 4 h after injection) was enough to cause both of these effects, which were observed following intracecal administration of barbaloin (31.1 mg/kg). These results together with our previous data, which showed a relationship between increase in the intestinal water content and the stimulation of peristalsis, confirm that AE-anthrone is the principal agent responsible for the cathartic effect of barbaloin. We also propose that the increase in water content is a more important factor than stimulation of peristalsis in the induction of diarrhea by barbaloin. Odes & Madar conducted a study to evaluate the effect of a novel laxative preparation, composed of Aloe vera and other herbal ingredients in patients with chronic constipation. Thirty-five men and women were randomized to receive capsules containing the Aloe vera formula, or placebo, in a double-blind trial lasting 28 days. Symptoms in the last 2 weeks of the treatment period were compared to those in the 14-day pre-trial basal period. In the Aloe vera group, bowel movements became more frequent, the stools were softer and laxative dependence was reduced. In the placebo group, all these parameters were unchanged. Abdominal pain was not reduced in either group. The results of this study show that the preparation is an effective laxative in the treatment of constipation.
This herb is widely used in India for treating a variety of disease. Also found in Bulgaria it is used for impotency. One of the major medicinal uses is as a urinary cleanser. It is a diuretic and helps eliminate toxins from the system.
This herb is widely utilized as a spice in Indian cooking. It is used for its flavor and carminative activity. The fruit of the plant is antispasmodic as well and a digestive. The seed, and especially the essential oil in the seed, is strongly antiseptic, antispasmodic, aromatic, bitter, diaphoretic, digestive, diuretic, expectorant and tonic. It is used internally in the treatment of colds, coughs, influenza, asthma, diarrhoea, cholera, colic, indigestion, wind, oedema, arthritis and rheumatism. The seed is harvested when fully ripe and either distilled for the essential oil or dried for later use.
The seed contains about 4 - 6% essential oil, of which 45 - 55% is the strongly antiseptic essential oil 'thymol. The essential oil is also added to cough medicines. The root is carminative and diuretic.
The leaves of the plant yield the most popular purgative. Sennosides are the most medicinally active purgatives and used in Modern medicine across the globe. Two aloe-emodin dianthrone diglucosides (I and II) were isolated from the leaves of Cassia angustifolia Vahl by successive column chromatography with Amberlite XAD-2, silica gel, Polyamide C-200 and Sephadex LH-20. The stereostructures of I and II were elucidated as trans and meso isomers at 10-10', respectively, from the patterns of the ultraviolet absorption spectra and circular dichroism curves. This is the first report of isolation of diglucoside I from senna. Despite the lack of purgative activity, diglucoside I exerts a potentiating effect of about 1.3 times on the purgative activity of sennoside A in mice when even 15% is included in the mixture. The difference between I and a third active glycoside based on aloe-emodin is also discussed.
Triphala is a combination of three fruits Terminalia chebula, Terminalia belerica and Emblica officinalis. In combination the fruits produce a mild laxative activity which synergizes that of the other ingredients.
Commonly known a Fig, the fruit of the fig tree is used in India and the Middle East as a cure for constipation. Fig extract has proven to be a mild safe laxative. The fruit is mildly laxative, demulcent, digestive and pectoral. The unripe green fruits are cooked with other foods as a galactogogue and tonic. Syrup of figs, made from the fruit, is a well-known and effective gentle laxative that is also suitable for the young and very old.